3/13/2014

IODINE DEFICIENCY? NOT ONLY GOITER AND MENTAL RETARDATION...


Iodine is a trace element, essential for thyroid function and for the prevention of goiter, but not only.

Iodine is fundamental for the proper development of the nervous system and iodine deficiency, in addition to being a major cause of mental retardation and neurological and cognitive deficits, is linked to an increased risk of developing  certain cancers, including thyroid cancer and breast cancer.



Iodine deficiency is widespread in developing countries , particularly in Africa , Central Asia and South- East Asia, but it is a collective interest problem even in industrialized countries . Even in Europe, in fact, there are countries "at risk" , known for being iodine deficient, including Germany , France, Belgium and Italy . In the latter it is estimated that about 6 million people (more than 10 % of the population) .suffer from goiter .



Why is Iodine so important ?
Because an insufficient intake of iodine can cause health problems in all age groups.

The clinical manifestations of iodine deficiency, or " iodine deficiency disorders " (IDD) , whose severity and symptoms are variable depending on the degree of iodine deficiency, are numerous.
While in adolescent and adult iodine deficiency is the main cause of goiter and anomalies related to the thyroid gland malfunction (hypothyroidism) , an inadequate intake of iodine in pregnant women or during breast-feeding can have very serious consequences on the health of infants and children .
Iodine deficiency in the mother and the resulting hypothyroidism can cause  irreversible neurological damage during fetal development and newborn’s growth.

The neurological damage can occur with hearing loss, learning disabilities , mental retardation and myelination disorders.

Mild iodine deficiency , such as those commonly found in Italy and Europe, can lead to minor learning disabilities and neurological problems in children.

Iodine deficiency is also considered a risk factor not only for the development of benign thyroid diseases, but even for thyroid cancer: in areas where goiter is endemic due to iodine deficiency, there is , unfortunately, an increased incidence of thyroid cancer.

Iodine deficiency is also linked to an increased incidence of benign or malignant breast tissue disorders, ranging from fibrocystic breast disease to breast cancer.


How much iodine do I need to stay healthy ?

To ensure proper thyroid function, the daily iodine requirement for adolescents and adults is 150 micrograms.
This requirement is increased in specific physiological conditions such as pregnancy and lactation, in order to ensure the normal development of the child.


Where is iodine ?
The main source of iodine for humans is diet.
In this regard, we have to highlight that the iodine content of foods is extremely variable depending on the ground in the case of foods of plant origin, depending on supply in case of foods of animal origin .
The main dietary sources of iodine are saltwater fish and shellfish, followed by eggs, milk and meat. Fruits and vegetables contain smaller iodine amounts.
But we must not forget that there are some foods , called goitrogenic foods or goitrogens , which can inhibit the absorption of dietary iodine.
Goitrogenic foods are mainly cabbage, turnips , broccoli (Brassicaceae or Cruciferae) and their goitrogenic effect is attributed to the content of isothiocyanates , molecules that bind iodine.
However, Cruciferae are not to be demonized , since they have anti-cancer properties and since their consumption in the average diet is "limited".

The average amount of iodine in the diet is insufficient to cover the daily requirement of iodine.


How can I satisfy my iodine requirements? Should I take dietary supplements of iodine?
In order to prevent iodine deficiency is sufficient to consume iodized salt (iodine –enriched salt) in place of common salt, as part of a varied and balanced diet.

Iodized salt has the same taste of common salt but provides 30 micrograms / gram of iodine (one fifth of the daily requirement for adults) , this allows an adequate iodine intake with a salt intake which don’t exceed the recommended limits .

Therefore, the intake of iodized salt is not in conflict with the reduction of salt intake to no more than 4-5 grams per day, recommended for the prevention of hypertension and cardiovascular disease.



On the health products market, dietary supplements with high amounts of iodine are available.

These, frequently algae-based, iodine supplements are marketed as slimming supplements and weight-loss aids, since iodine increases thyroid function and consequently metabolism.


These iodine supplements should always be used with caution and preferably under medical supervision. An excessive iodine intake may in fact aggravate a possible hyperthyroidism, even leading to serious consequences for your health.

I often eat at restaurants or out of home. Should I ask for iodized salt ?
Nowadays there should be no need.
We have to remember that the World Health Organization (WHO) recommends the use of iodized salt (ie enriched in iodine ) in the preparation of food with the aim of iodine deficiency disorders eradication.

So, in conclusion, in order to prevent iodine deficiency ... a little salt, but always iodized ...



Sources:
Iodine deficiency in pregnancy and the effects of maternal iodine supplementation on the offspring: a review; Michael B Zimmermann, Am J Clin Nutr 2009;89(suppl):668S–72S.
Iodine: Deficiency and Therapeutic Considerations, Lyn Patrick, ND, Alternative Medicine Review Volume 13, Number 2 2008
Iodio e Salute, Gruppo di Lavoro per l’attuazione della legge 21 marzo 2005, n.55 “Disposizioni finalizzate alla prevenzione del gozzo endemico ed altre patologie da carenza iodica” operativo presso il Ministero della Salute.
Image Courtesy of voraorn/FreeDigitalPhotos.net



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